ARIA
AdaptiveRiskIntelligenceforPolypharmacyAssessment

An AI agent system that goes beyond detecting drug interactions. It reasons through temporal modeling, mechanistic explanation, personalized risk scoring, and actionable deprescribing, all within a single integrated pipeline.

Eight Capabilities

Clinical reasoning features that do not exist in any other tool available today.

Temporal Cascade Modeling

Predicts when an interaction will peak, not just whether it exists.

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Mechanistic Reasoning

Explains interactions at the molecular level through CYP pathways and renal clearance.

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Patient Phenotype Scoring

Calculates personalized risk adjusted for age, kidney function, and clinical history.

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N-Drug Interaction Graph

Detects emergent three-drug interactions that pairwise checkers miss entirely.

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Evidence Grading

Tags every alert with a confidence score and links to PubMed citations.

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Deprescribing Optimizer

Generates a prioritized plan with substitutions and expected risk reduction at each step.

Ready to Analyze?

Enter a medication list and patient context. ARIA will reason through every interaction, calculate personalized risk, and generate a structured clinical report.